Fermented wheat germ extract (Avemar) in the treatment of cancer and autoimmune diseases
L. G. Boros, M. Nichelatti, Y. Shoenfeld
Annals of the New York Academy of Sciences, 2005
Abstract
Avemar, the product of industrial fermentation of wheat germ, possesses unique cancer-fighting characteristics. Taken orally, Avemar can inhibit metastatic tumor dissemination and proliferation during and after chemotherapy, surgery, or radiation. Benefits of Avemar treatment have been shown in various human cancers, in cultures of in vitro grown cancer cells, in the prevention of chemical carcinogenesis, and also in some autoimmune conditions. This document reviews the clinical and experimental results obt (»)
Metabolic Profiling of Cell Growth and Death in Cancer: Applications in Drug Discovery
L. G. Boros, M. Cascante, W. Paul Lee
Drug Discovery Today, 2002
Abstract
Metabolic profiling using stable-isotope tracer technology enables the measurement of substrate redistribution within major metabolic pathways in living cells. This technique has been demonstrated that tranformed human cells exhibit profound metabolic shifts and that some and anti-cancer drugs produce their effects by forcing a reversion of these metabolic changes. By revealing tumor-specific metabolic shifts in tumor cells, metabolic profiling enables drug developers to identify the metabolic steps that co (»)