Journal of Experimental and Clinical Cancer Research

Journal of Experimental & Clinical Cancer Research is an online peer-reviewed journal that provides a high-quality forum for basic, clinical and translational work in oncology.

The journal publishes scientific studies on the immunological, epidemiological, pathological, biological and clinical aspects of oncology. Topics considered range from molecular genetics via infectious agents to surgery and therapeutic approaches and outcomes. Systematic reviews of clinical and basic research, as well as clinical practice guidelines, are especially welcome.

Title abbreviation
J Exp Clin Cancer Res
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Promising cytotoxic activity profile of fermented wheat germ extract (Avemar) in human cancer cell lines

Fermented wheat germ extract (FWGE) is currently used as nutrition supplement for cancer patients. Limited recent data suggest antiproliferative, antimetastatic and immunological effects which were at least in part exerted by two quinones, 2-methoxy benzoquinone and 2,6-dimethoxybenzquinone as ingredients of FWGE. These activity data prompted us to further evaluate the in vitro antiproliferative activity of FWGE alone or in combination with the commonly used cytotoxic drugs 5-FU, oxaliplatin or irinotecan in a broad spectrum of human tumor cell lines.

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